Modern aspects of pathogenesis of comorbidity of non-alcoholic fatty liver disease and hypertension in the presence or absence of chronic kidney disease.

The article presents the main aspects of pathogenesis comorbidity non-alcoholic fatty liver disease and hypertension. These diseases are very often presented as comorbidities in a large number patients can independently impair renal function. According to literature results our own research, role insulin resistance, disorders lipid carbohydrate metabolism, cytokine imbalance, antioxidant defense system this was analyzed. effect hypoadictinemia increased blood levels fetuin-A cytokeratin-18 on also assessed. independent function, arterial stiffness occurrence diastolic heart function interaction between hypertension depending presence chronic kidney evaluated. Key words: nonalcoholic disease, hypertension, pathogenesis, comorbidity, impairment.